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Development status and trend of drug packaging

2024/1/4

Everyone has used drugs, but they may not know much about the packaging and related knowledge of drugs. Therefore, there may be many misunderstandings when purchasing drugs. Like many products, drugs, as a special commodity, are related to the life safety of people and animals, so they also have special requirements for packaging.

Drugs include chemicals (western medicine), mixed preparations (Chinese patent medicine), biological preparations and so on. Due to the diversity of drug classification and dosage forms; The scale of pharmaceutical enterprises is large and small, the strength is strong and weak, and the degree of attention to packaging is high and low; In some enterprises, the whole packaging process is made in auto production line, while in others, it is a combination of machinery and manual operation, and all of them are completed by manual operation. In addition, the different printing and packaging materials make the packaging quality of drugs varied and colorful, so as to meet the needs of different drugs and patients at different levels. There are prescription drugs and over-the-counter drugs, including tablets, pills, capsules, granules, oral preparations, powder injections, injections, etc. There are concentrated pills, honey pills, honey pills, water pills, etc. Different drugs have different characteristics, so there are different requirements for packaging. At present, the common forms of drug packaging in the market are bags, bottles, aluminum-plastic plates and tubes. According to the different materials, there are plastic bags, aluminum-plastic composite bags, bottled plastic bottles, glass bottles and so on. Some enterprises attach importance to the packaging of products, and the packaging is more distinctive. For example, the pharmaceutical packaging in Xi 'an Yangsen is very formal. Another example is the series packaging of Chinese medicine concentrated pills of Changsha Jiuzhitang Pharmaceutical Co., Ltd., and the inner packaging uses polyester bottles; However, the packaging of concentrated pills in Wanxi Pharmaceutical Factory in Henan Province is different. They use a flat high-density polyethylene plastic bottle with a unique opening, and the outer box is a box with a horizontal structure, which is obviously different from similar varieties, and the product grade is obviously improved. Xi 'an Zhengda Pharmaceutical Co., Ltd. has a double-body packaging form, while the same kind of drugs in the market are packaged in a single bottle. These are some well-made packages, which are unusual, novel and unique and can leave a deep impression on people. Of course, there are many companies in the market that have done a good job in packaging, such as the drug packaging of Beijing Tongrentang Pharmaceutical Company, which is characterized by antique. On the contrary, some packages are relatively poor and will not leave any impression on people, no matter the materials used in packaging, packaging technology, decoration and printing are relatively backward. Of course, this is related to the scale and strength of the enterprise. Because of the rough packaging, no matter how good the medicine is, it will also affect the sales of the medicine. After all, the time when wine is not afraid of the depth of the alley has passed. In recent years, pharmacies have mushroomed in major cities, especially after the separation of medicines and the reform of medical insurance system, most people prefer to buy the same medicine in pharmacies rather than hospitals, which gives them greater freedom and more and stronger choices. Consumers go to pharmacies to buy drugs. For ordinary otc drugs, they all like to buy drugs with complete packaging, detailed content introduction and regular manufacturers. The quality of drugs can be seen from the packaging. Therefore, in the pop market, the packaging of drugs is very important and the promotion effect is even greater. The country is now vigorously rectifying the pharmaceutical market, and the packaging requirements for drugs are becoming more and more strict. From last year to this year, several rectification notices were issued, ordering pharmaceutical enterprises to make corrections within a time limit and standardize the packaging form. Therefore, pharmaceutical companies are paying more and more attention to the packaging of drugs and are facing great changes.

In the sales market, there are not many patients who can explain clearly what kind of drugs are well packaged and what kind of drugs are not well packaged. Due to the individual differences of patients and the severity of diseases, different patients may have different standards and different requirements for packaging. Patients want to buy drugs with good curative effect, relatively economical and reasonable packaging, and "cheap and good quality". Proper packaging is very necessary.

At present, there are still many deficiencies and defects in drug packaging. For example, many manufacturers use pvc double-layer heat sealing for the inner packaging material of Chinese patent medicine Damiwan dosage form. Because of the tight seal, it is difficult for patients to open it, so they must resort to auxiliary tools. In addition, manufacturers usually use glass bottles or plastic bottles for the packaging of traditional Chinese medicine honey pills, and the quantity and dosage are expressed in grams, but the packaging does not indicate how many pills 1g is. Patients do not know how many pills to take, so they can only rely on estimation, which is inconvenient and unsafe to take. As far as the packaging text of drugs is concerned, some of the contents that should be there are not, but many words that patients can't understand are printed; Some packaging words are too simple and some are too specialized, especially the packaging words of traditional Chinese medicine products are too professional for patients to understand. After all, packaging serves drugs and should be welcomed by patients. If patients take it by mistake or take it inconvenient because of improper expression of packaging or packaging words, it will not be worth the loss for enterprises, and there are many similar problems. Packaging is very important, but it is not advisable to pursue packaging unilaterally, and it is not advisable to use exquisite and expensive packaging materials in an attempt to improve the quality of drugs without paying attention to the quality of drugs. I don't understand the overall function of packaging, and as a result, drugs are not popular with patients. Packaging has gone far beyond its basic function, but it gives people a sense of being flashy and usurping the host's role. In fact, it is a kind of excess packaging, which is difficult to win the trust of consumers, lacks the motivation for long-term development, and is a waste of packaging resources. I believe these problems will be solved in the near future. 

The same drug, the same dosage form, and the packaging of different manufacturers are also different. For example, the same capsule is packed in aluminum-plastic blister and bottled, with good and bad materials. The same drug may have several specifications and packaging, and the decoration may be different. Of course, this is related to enterprises and the needs of businesses and consumers. Because of the fierce competition of drugs, the pharmaceutical packaging manufacturing industry is also competing. The laws and regulations on drugs require more and more strict drug packaging materials. There are more than a dozen items on the drug packaging labels, and none of them can be less. They must be printed or labeled with instructions in accordance with regulations. The label or description must indicate the generic name, ingredients, specifications, manufacturer, approval number, product batch number, production date, expiration date, indications or functional indications, usage, dosage, contraindications, adverse reactions and precautions of the drug. The labels of narcotic drugs, toxic drugs for medical use, radioactive drugs, drugs for external use and over-the-counter drugs must bear the prescribed marks. Some also have bar codes, anti-counterfeiting labels and other content. The packaging of regular manufacturers generally includes packaging bottles, bottle labels, instructions, outer boxes, sealed labels of finished products, etc. The instructions of drugs are prepared in strict accordance with the contents approved by National Medical Products Administration, and no unapproved contents can be published. The writing format and contents should be printed in accordance with the prescribed format.

The above situation, I hope to be helpful to consumers when purchasing drugs, and to distinguish the quality and authenticity of drugs by packaging. Although there are some problems in the pharmaceutical packaging market at present, in the near future.

Second, the development of drug packaging and future 

Like other industries, the pharmaceutical packaging industry has made great progress in recent years, especially the improvement of packaging manufacturing technology, which has laid a good foundation for the development of pharmaceutical packaging, the export of drugs and the world.

First of all, the speed of upgrading pharmaceutical packaging materials and containers has been accelerated, backward packaging materials, containers and old equipment and technologies have been gradually eliminated, advanced technologies, equipment and packaging materials have been continuously applied to drug packaging, and the packaging awareness of pharmaceutical enterprises has been continuously strengthened, and drug packaging has shown a good development momentum. 

In the selection of new materials, the materials of bagged pills are changed from paper bags and paper-plastic bags to aluminum-plastic bags and pearl film bags. Ptp blister packaging is changed from aluminum-plastic blister to double aluminum blister packaging, which has better sealing performance; High-density polyethylene plastic bottles, polyester plastic bottles and other quality properties have been replaced by very good plastic bottles; The packaging form of pvc heat sealing of traditional Chinese medicine honey pill will also be replaced by aluminum-plastic blister packaging. The glass bottle and the process of sealing with bakelite wax have been eliminated, and aluminum foil and other materials are used to seal it, which has better sealing performance and higher production efficiency. Tear holes have also been added to bagged drugs. In the past, there were no instructions in the packaging of some drugs, and the label content was incomplete. Now it has been added. Originally, patients felt that it was inconvenient to use drugs. Because of the change of packaging, patients' impression of drugs has also changed greatly.

With the fierce market competition and the development of gmp in China's pharmaceutical industry, some major packaging machinery manufacturers have developed, researched and introduced many advanced automatic drug packaging machines, such as ptp blister packaging machine, automatic capsule filling machine, aluminum foil sealing machine, automatic box filling machine and other automatic packaging equipment. More and more manufacturers have changed from manual packaging to automatic assembly line packaging, which has greatly improved the quality of drugs and improved the grade of drug packaging.

Due to the introduction of ci concept and its infiltration and spread in various fields, great changes have taken place in the packaging and decoration of drugs. The traditional design techniques have been replaced by advanced computerized design software, and the traditional color application rules (such as warm colors for nourishing nutrition; Cold color and light color for relieving pain and diminishing inflammation have been gradually broken. Is the same variety, the same dosage form, each manufacturer's packaging and decoration is also different, irregular to find, each has its own personality. Moreover, the decoration design of traditional Chinese medicine has a tendency to return to nature, and it is developing towards western-style design. Packaging design has also changed from traditional manual drafting to computer design. It has realized the one-stop service system of design, plate making and printing, and the work is more convenient and fast. In the market, the packaging factors that are wildly popular and disorganized and have nothing to do with drugs are gradually abandoned, and there are more and more personalized and unified packaging forms, which are easy to identify and have personality and adapt to patients' psychology. For example: tend to use green, etc. Due to the application of vis concept in drug packaging, it not only forms a unique packaging design system for each enterprise, but also effectively prevents counterfeit and shoddy drugs. What is fashionable today may be out of date tomorrow. Therefore, the sales packaging of goods must be constantly improved, and balance, harmony and unity must be sought in inheriting tradition and creativity. The impression of packaging is the impression of drugs and the impression of enterprises. Under the condition of the same quality of drugs, the style of packaging and the quality of materials play a great role in promoting drugs. As a pharmaceutical enterprise, while constantly improving the quality of drugs and developing new drugs, it is also constantly studying which packaging can be more consistent with drugs. More loved by patients.

We can predict that the future drug packaging will be more detailed and standardized, and will develop in the direction of serialization, reflecting the unique product image system of pharmaceutical enterprises and the level of China's pharmaceutical packaging industry, and producing drugs that patients can use with confidence. More diversified and better barrier and artistic printing technology are needed for drug packaging, and anti-piracy, anti-theft and anti-theft are required.